Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24241213 | 0.74 | MAPT (0.61) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13246749 | 0.70 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9616922 | 0.67 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10763870 | 0.65 | MAPT (0.61) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1613425 | 0.65 | MAPT (0.47) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9442571 | 0.62 | — | — | |
| SCHEMBL8766715 | 0.61 | MAPT (0.38) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15942164 | 0.61 | MAPT (0.55) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11239388 | 0.61 | MAPT (0.50) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4631766 | 0.61 | MAPT (0.50) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239092-A | Process for producing furylpropargylcarbinol and derivative thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-08-24 | — | — | US | disclosed |
| US-5189186-A | Dehydrohalogenation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-02-23 | — | — | US | disclosed |