Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | AKT1 | P31749 | 7/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | AKT2 | P31751 | 1/20 | 0.52 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.52 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616806 | 0.98 | KDM4E (0.55) | KDM4ERAB9AAKT1PDPK1ABCB11 | |
| SCHEMBL10589216 | 0.82 | AKT1 (0.42) | KDM4ERAB9AAKT1PDPK1ABCB11 | |
| SCHEMBL10162230 | 0.80 | NPC1 (0.45) | RAB9AAKT1MEN1MAPTKMT2A | |
| SCHEMBL8742612 | 0.79 | KDM4E (0.78) | KDM4ERAB9AHSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL9566995 | 0.78 | RAB9A (0.54) | KDM4ERAB9AALDH1A1MAPTHPGD | |
| SCHEMBL9566994 | 0.78 | RAB9A (0.54) | KDM4ERAB9AALDH1A1MAPTHPGD | |
| SCHEMBL10589213 | 0.78 | PTPN11 (0.44) | KDM4ERAB9AAKT1PDPK1ABCB11 | |
| SCHEMBL15164269 | 0.77 | KDM4E (0.76) | KDM4ERAB9AHSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL15164268 | 0.77 | KDM4E (0.76) | KDM4ERAB9AHSD11B1HSD17B10ALDH1A1 | |
| SCHEMBL8742541 | 0.77 | KDM4E (0.76) | KDM4ERAB9AHSD11B1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309514-B1 | MEDIA CONTAINING DERIVATIVES OF THIAZOLE AND THIADIAZOLE, WITH SMECTIC LIQUID-CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1992-12-02 | — | — | EP | disclosed |
| EP-0309514-A1 | MEDIA CONTAINING DERIVATIVES OF THIAZOLE AND THIADIAZOLE, WITH SMECTIC LIQUID-CRYSTAL PHASE. | MERCK PATENT GMBH (DE) | 1989-04-05 | — | — | EP | disclosed |
| WO-1988008019-A1 | MEDIA CONTAINING DERIVATIVES OF THIAZOLE AND THIADIAZOLE, WITH SMECTIC LIQUID-CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-20 | — | — | WO | disclosed |