SCHEMBL9617339

SCHEMBL9617339

[N]=C=CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.52
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ARG2 P78540 1/20 0.40
CALM1 P0DP23 1/20 0.39
ALDH1A1 P00352 3/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP1B1 Q16678 1/20 0.38
IDO1 P14902 5/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
TSHR P16473 3/20 0.36
TP53 P04637 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
TRPA1 O75762 1/20 0.36
MAOA P21397 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27553369 0.78 MAOB (0.44) MAOBCA1CA2ARG2CALM1
SCHEMBL861788 0.77 MAOB (0.55) MAOBCA1CA2ARG2CALM1
SCHEMBL28936724 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL11349290 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL3042523 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL3042520 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL29094387 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL57808 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL15282878 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1
SCHEMBL460253 0.75 MAOB (0.52) MAOBCA1CA2ARG2CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4029972-A None JP disclosed
JP-H0429972-A NEW PRODUCTION OF 2,6-DIMETHYL-4-(M-NITROPHENYL)-1,4-DIHYDROPYRIDINE COMPOUND TOKAWA TETSUO 1992-01-31 JP disclosed