Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730171 | 0.83 | IDO1 (0.39) | MAOAMAOB | |
| SCHEMBL11787507 | 0.81 | CHRNB2 (0.36) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6129136 | 0.81 | IDO1 (0.37) | ANPEP | |
| SCHEMBL8352284 | 0.72 | KDM1A (0.40) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6129139 | 0.69 | KDM1A (0.35) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1193046 | 0.69 | ANPEP (0.39) | ANPEPMAOA | |
| SCHEMBL4703520 | 0.68 | ACP3 (0.44) | HTR2A | |
| SCHEMBL8445624 | 0.66 | IDO1 (0.42) | MAOAMAOB | |
| SCHEMBL30523117 | 0.66 | IDO1 (0.42) | MAOAMAOB | |
| SCHEMBL1148775 | 0.66 | IDO1 (0.42) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4230354-A | — | — | None | — | — | JP | disclosed |
| JP-H04230354-A | AROMATIC DIISOCYANATOINDANE DERIVATIVE AND ITS PRODUCTION | MITSUI TOATSU CHEM INC | 1992-08-19 | — | — | JP | disclosed |