Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HK2 | P52789 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226897 | 0.84 | CYP3A4 (0.56) | CYP3A4LMNAMAPK1USP2SMN1; SMN2 | |
| Isotorachrysone SCHEMBL16226209 | 0.82 | CYP3A4 (0.47) | IDO1CYP3A4LMNAMAPK1USP2 | |
| SCHEMBL20020937 | 0.78 | MAPT (0.47) | CYP3A4LMNAGAA | |
| Torachrysone SCHEMBL29380720 | 0.76 | CYP3A4 (0.51) | IDO1CYP3A4MAPK1USP2SMN1; SMN2 | |
| Torachrysone SCHEMBL932035 | 0.76 | CYP3A4 (0.51) | IDO1CYP3A4MAPK1USP2SMN1; SMN2 | |
| SCHEMBL29664473 | 0.75 | CYP3A4 (0.58) | CYP3A4LMNAMAPK1USP2SMN1; SMN2 | |
| SCHEMBL2023385 | 0.75 | GAA (0.51) | CYP3A4LMNAMAPK1USP2SMN1; SMN2 | |
| SCHEMBL16226426 | 0.75 | CYP3A4 (0.50) | CYP3A4LMNAMAPK1USP2SMN1; SMN2 | |
| SCHEMBL16226383 | 0.74 | CYP3A4 (0.49) | CYP3A4LMNAMAPK1USP2SMN1; SMN2 | |
| SCHEMBL11321057 | 0.72 | CYP3A4 (0.54) | CYP3A4LMNAMAPK1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4234340-A | — | — | None | — | — | JP | disclosed |
| JP-H04234340-A | NOVEL FERMENTATION PRODUCT HAVING ACTIVITY AGAINST PARASITE | MERCK & CO INC | 1992-08-24 | — | — | JP | disclosed |