Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962042 | 1.00 | PTGIR (0.55) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL3747302 | 1.00 | PTGIR (0.55) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11722144 | 0.91 | MEN1 (0.62) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11723081 | 0.91 | MEN1 (0.62) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11727227 | 0.91 | MEN1 (0.62) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11723075 | 0.91 | MEN1 (0.62) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11722150 | 0.91 | MEN1 (0.62) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11727235 | 0.91 | MEN1 (0.62) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11719594 | 0.87 | MEN1 (0.66) | PTGIRMEN1KMT2AGALR3PTGER2 | |
| SCHEMBL11721670 | 0.87 | MEN1 (0.66) | PTGIRMEN1KMT2AGALR3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501793-B2 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-08-06 | — | — | US | disclosed |
| US-20110015238-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-7833995-B2 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20070129327-A1 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | disclosed |
| EP-1707208-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129327-A1 | Blood flow promoters for cauda equina tissues | PTGFR, PTGIS, PTGIR | PTGIR 3/4885MEN1 4761/4885KMT2A 1776/4885 |
| US-20110015238-A1 | BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES | PTGFR, PTGIS, PTGIR | PTGIR 3/4885MEN1 4761/4885KMT2A 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.