Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298046 | 0.92 | SMN1; SMN2 (0.43) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL10424987 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL14632314 | 0.83 | MAPT (0.50) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13006945 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL20226244 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL7132447 | 0.80 | DRD2 (0.52) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17038794 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL8015992 | 0.79 | TDP1 (0.50) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15431171 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL20024179 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4036290-A | — | — | None | — | — | JP | disclosed |
| US-20110034626-A1 | COATING COMPOSITION AND COATED ARTICLE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| JP-H0436290-A | SILANE COMPOUND | TOAGOSEI CHEM IND CO LTD | 1992-02-06 | — | — | JP | disclosed |