Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12149774 | 0.79 | TYMP (0.38) | TYMPNPC1LMNAATAD2SMN1; SMN2 | |
| SCHEMBL1271158 | 0.74 | GDA (0.32) | TYMPGDA | |
| SCHEMBL9617668 | 0.72 | — | — | |
| SCHEMBL11616197 | 0.69 | JAK2 (0.46) | TYMPNPC1LMNAATAD2SMN1; SMN2 | |
| SCHEMBL1270735 | 0.68 | JAK2 (0.57) | TYMPLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1270724 | 0.68 | TYMP (0.32) | TYMP | |
| SCHEMBL2832577 | 0.68 | TYMP (0.46) | TYMPATAD2ALDH1A1GDAKDM4E | |
| SCHEMBL1445690 | 0.67 | TYMP (0.56) | TYMPNPC1LMNAATAD2SMN1; SMN2 | |
| SCHEMBL12900039 | 0.67 | JAK2 (0.41) | TYMPLMNAKMT2AMEN1 | |
| SCHEMBL1271870 | 0.66 | DAO (0.31) | TYMPDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4261161-A | — | — | None | — | — | JP | disclosed |
| JP-H04261161-A | FLUOROALKYL GROUP-CONTAINING PYRIMIDINE DERIVATIVE AND PRODUCTION THEREOF | AGENCY OF IND SCIENCE & TECHNOL | 1992-09-17 | — | — | JP | disclosed |