Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313243 | 0.82 | TSHR (0.44) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL11499036 | 0.80 | TSHR (0.45) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL11875067 | 0.80 | MEN1 (0.40) | TSHRGABRA1GABRB2CYP2C19ALDH1A1 | |
| SCHEMBL11576154 | 0.78 | CYP2C19 (0.39) | CYP2C19SMN1; SMN2 | |
| SCHEMBL13458364 | 0.78 | TSHR (0.44) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL9287878 | 0.78 | POLB (0.44) | TSHRGABRA1GABRB2CYP2C19POLB | |
| SCHEMBL9749736 | 0.77 | TSHR (0.42) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL11437594 | 0.77 | TSHR (0.62) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL7600327 | 0.76 | SMN1; SMN2 (0.34) | TSHRCYP2C19ACHEHPGDSMN1; SMN2 | |
| SCHEMBL11030025 | 0.75 | TSHR (0.38) | TSHRGABRA1GABRB2CYP2C19ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62225237-A | — | — | None | — | — | JP | disclosed |
| JP-55145626-A | — | — | None | — | — | JP | disclosed |
| JP-4264048-A | — | — | None | — | — | JP | disclosed |
| JP-1011630-A | — | — | None | — | — | JP | disclosed |
| JP-H04264048-A | TRIFLUOROMETHYL COMPOUND | CHISSO CORP | 1992-09-18 | — | — | JP | disclosed |
| JP-S6411630-A | EMULSIFYING AGENT FOR DISPERSION OF AQUEOUS RESIN | DAI ICHI KOGYO SEIYAKU CO LTD | 1989-01-17 | — | — | JP | disclosed |
| JP-S62225237-A | EMULSIFIER FOR WATER-BASED RESIN DISPERSION | DAI ICHI KOGYO SEIYAKU CO LTD | 1987-10-03 | — | — | JP | disclosed |
| JP-S55145626-A | NEW PHENOL DERIVATIVE | YOTSUKAICHI GOSEI KK | 1980-11-13 | — | — | JP | disclosed |