Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458364 | 0.82 | TSHR (0.44) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL265240 | 0.81 | TSHR (0.47) | TSHRGABRA1GABRB2POLBALOX15 | |
| SCHEMBL11499036 | 0.80 | TSHR (0.45) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL5934663 | 0.77 | TSHR (0.50) | TSHRGABRA1GABRB2POLBALOX15 | |
| SCHEMBL31444491 | 0.77 | NISCH (0.44) | TSHRCYP2C19PDCD1LG2CD274KDM4E | |
| SCHEMBL11437594 | 0.77 | TSHR (0.62) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL8995483 | 0.77 | ESR1 (0.41) | TSHRCYP2C19ACHEPDCD1LG2CD274 | |
| SCHEMBL19332982 | 0.77 | CYP2C19 (0.38) | CYP2C19PDCD1LG2CD274ALDH1A1CYP3A4 | |
| SCHEMBL9617748 | 0.77 | TSHR (0.42) | TSHRGABRA1GABRB2CYP2C19ACHE | |
| SCHEMBL2328835 | 0.77 | CYP2C19 (0.38) | CYP2C19PDCD1LG2CD274ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61160763-A | — | — | None | — | — | JP | disclosed |
| JP-61172153-A | — | — | None | — | — | JP | disclosed |
| JP-4282644-A | — | — | None | — | — | JP | disclosed |
| JP-H04282644-A | IMAGE FORMING METHOD | RICOH CO LTD | 1992-10-07 | — | — | JP | disclosed |
| JP-S61172153-A | TONER FOR DEVELOPING ELECTROSTATIC CHARGE IMAGE | CANON INC | 1986-08-02 | — | — | JP | disclosed |
| JP-S61160763-A | ELECTROSTATIC CHARGE APPLYING MEMBER FOR DEVELOPING ELECTROSTATIC CHARGE IMAGE | CANON INC | 1986-07-21 | — | — | JP | disclosed |