SCHEMBL9617847

SCHEMBL9617847

Cc1c(Br)c(=O)[nH]c(=O)n1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
POLB P06746 1/20 0.44
GLA P06280 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.41
ATM Q13315 2/20 0.40
GAA P10253 2/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 2/20 0.36
TYMP P19971 3/20 0.35
PNP P00491 1/20 0.35
DAO P14920 1/20 0.32
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
CSNK2A1 P68400 1/20 0.31
PDE3B Q13370 2/20 0.31
PDE3A Q14432 2/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1738351 0.76 CSNK2A2 (0.45) MAPTPOLBGLATDP1ALDH1A1
SCHEMBL9617992 0.71 MAPT (0.47) MAPTPOLBGLATDP1ALDH1A1
SCHEMBL11122898 0.66 MAPT (0.69) MAPTPOLBGLAALDH1A1ATM
SCHEMBL6013388 0.65 MAPT (0.59) MAPTPOLBGLATDP1ALDH1A1
SCHEMBL8592123 0.60 KDM4E (0.32) KMT2ATYMPKDM4E
SCHEMBL3480363 0.59 ALDH1A1 (0.38) GLATDP1ALDH1A1TYMPPNP
SCHEMBL400005 0.58 TDP1 (1.00) POLBTDP1ALDH1A1GAAKMT2A
SCHEMBL9592609 0.58 EPHX2 (0.42) MAPTPOLBGLAALDH1A1ATM
SCHEMBL15666274 0.58 CSNK2A2 (0.41) MAPTPOLBGLATDP1ALDH1A1
SCHEMBL15218133 0.56 GDA (0.39) MAPTGLATDP1ALDH1A1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4275279-A None JP disclosed
JP-H04275279-A 1-AMINO-5-HALOGENO-6-SUBSTITUTED URACIL YAMASA SHOYU CO LTD 1992-09-30 JP disclosed