Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.66 |
| ▸ | MAOB | P27338 | 5/20 | 0.66 |
| ▸ | MAOA | P21397 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842883 | 0.84 | PTPN1 (0.75) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL96940 | 0.84 | PTPN1 (0.75) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL127924 | 0.79 | PTPN1 (1.00) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL29952282 | 0.79 | PTPN1 (1.00) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL2475452 | 0.73 | PTPN1 (0.59) | PTPN1MAOBMAOAPOLBPTPN2 | |
| Thiosemicarbazide SCHEMBL28340570 | 0.72 | PTPN1 (0.74) | PTPN1MAOBMAOAPOLBPTPN2 | |
| SCHEMBL8786731 | 0.71 | MAOB (0.39) | PTPN1MAOBMAOAPIM1ALDH1A1 | |
| SCHEMBL11394269 | 0.71 | MAOB (0.39) | PTPN1MAOBMAOAPIM1ALDH1A1 | |
| SCHEMBL28170952 | 0.71 | MAOB (0.39) | PTPN1MAOBMAOAPIM1ALDH1A1 | |
| SCHEMBL2559161 | 0.70 | MAPT (0.57) | PTPN1MAOBMAOAPOLBPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62201967-A | — | — | None | — | — | JP | disclosed |
| JP-4279580-A | — | — | None | — | — | JP | disclosed |
| JP-H04279580-A | CHROMONE-BASED COMPOUND | MITSUBISHI KASEI CORP | 1992-10-05 | — | — | JP | disclosed |
| JP-S62201967-A | DIARYLMETHANE COMPOUND | MITSUBISHI CHEM IND LTD | 1987-09-05 | — | — | JP | disclosed |