Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176117 | 0.89 | NR4A2 (0.54) | MEN1KMT2AHTTNR4A2MAPT | |
| SCHEMBL7533377 | 0.83 | HTT (0.49) | MEN1KMT2AHTTNR4A2MAPT | |
| SCHEMBL3088415 | 0.83 | MEN1 (0.50) | MEN1KMT2AMAPTMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL3395899 | 0.82 | MEN1 (0.48) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL24654554 | 0.80 | MEN1 (0.41) | MEN1KMT2AHTTNR4A2MAPT | |
| SCHEMBL6414632 | 0.80 | KMT2A (0.52) | MEN1KMT2AMAPTMAPK1PKM | |
| SCHEMBL18950681 | 0.80 | CA12 (0.52) | MEN1KMT2AMAPTIDO1LMNA | |
| SCHEMBL18950695 | 0.79 | MEN1 (0.43) | MEN1KMT2AHTTMAPTMAPK1 | |
| SCHEMBL1000493 | 0.79 | MEN1 (0.53) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL29353825 | 0.79 | MEN1 (0.53) | MEN1KMT2AMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4321647-A | — | — | None | — | — | JP | disclosed |
| WO-2008024481-A2 | 3,4-DIHYDRO-2 (1H) - QUINOLINONE AND 2 (1H)-QUINOLINONE DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| JP-H04321647-A | DICHLOROPHENYLPROPYLAMINE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | MITSUBISHI GAS CHEM CO INC | 1992-11-11 | — | — | JP | disclosed |