Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069882 | 0.88 | NR4A2 (0.53) | HTTIDO1MAPTMEN1KMT2A | |
| SCHEMBL9421891 | 0.86 | MAPT (0.52) | HTTIDO1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28958615 | 0.86 | NR4A2 (0.51) | HTTIDO1MAPTMEN1KMT2A | |
| SCHEMBL28732815 | 0.84 | ABL1 (0.49) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11512622 | 0.84 | IDO1 (0.55) | HTTIDO1MAPTSIGMAR1ADRA2B | |
| SCHEMBL9618236 | 0.83 | MEN1 (0.47) | HTTIDO1MAPTMEN1KMT2A | |
| SCHEMBL1116563 | 0.82 | IDO1 (0.48) | HTTIDO1MAPTMEN1KMT2A | |
| SCHEMBL20159233 | 0.81 | TAAR1 (0.52) | HTTIDO1MAPTMEN1KMT2A | |
| SCHEMBL11505439 | 0.80 | MAPT (0.47) | HTTIDO1MAPTMEN1KMT2A | |
| SCHEMBL11842072 | 0.78 | MAPT (0.46) | HTTIDO1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118829-A1 | HETEROCYCLIC COMPOUNDS AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |
| US-8470805-B2 | Processes for preparing piperazinium salts of KMUP and use thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-06-25 | — | — | US | disclosed |
| US-20110136767-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-06-09 | — | — | US | disclosed |
| US-20020137740-A1 | Aminothiazole derivatives, process for preparing them and pharmaceutical compositions containing them | FONTAINE EVELYNE (FR) | 2002-09-26 | — | — | US | disclosed |
| EP-0934290-B1 | AMINOTHIAZOLE DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2002-04-17 | — | — | EP | disclosed |
| US-6344470-B1 | Aminothiazole derivatives, method of preparation and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-02-05 | — | — | US | disclosed |
| US-4154945-A | Fungicidal substituted imidazoles | THE BOOTS COMPANY LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4080462-A | Fungicidal compositions containing substituted imidazoles | THE BOOTS COMPANY LIMITED (EN) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136767-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | U2SURP, RRP15, KYNU | HTT 4049/4885IDO1 2079/4885MAPT 3853/4885 |
| US-20020137740-A1 | Aminothiazole derivatives, process for preparing them and pharmaceutical compositions containing them | CRHR1, ADRA1D, ADRB1 | HTT 1902/4885IDO1 797/4885MAPT 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.