Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.67 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.67 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.67 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.67 |
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697155 | 0.83 | GRIN2B (0.67) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL16702044 | 0.82 | GRIN2B (0.65) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| Iodide SCHEMBL28653084 | 0.82 | GRIN2B (0.65) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL5586439 | 0.82 | GRIN2B (0.65) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL28128817 | 0.80 | GRIN2B (0.62) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL1275831 | 0.80 | GRIN2B (1.00) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL3692033 | 0.79 | GRIN2B (0.61) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL9633313 | 0.79 | GRIN2B (0.61) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL18690743 | 0.79 | SCN2A (0.63) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL14058806 | 0.79 | GRIN2B (0.61) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4297449-A | — | — | None | — | — | JP | disclosed |
| JP-H04297449-A | N-HYDROXYBENZYLGUANIDINE DERIVATIVE AND GERMICIDE FOR AGRICULTURE AND HORTICULTURE | HOKKO CHEM IND CO LTD | 1992-10-21 | — | — | JP | disclosed |