Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.67 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.67 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.67 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.67 |
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28653084 | 0.98 | GRIN2B (0.65) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL9618307 | 0.83 | GRIN2B (0.67) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL5586439 | 0.82 | GRIN2B (0.65) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL16702044 | 0.82 | GRIN2B (0.65) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL28128817 | 0.80 | GRIN2B (0.62) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL1275831 | 0.80 | GRIN2B (1.00) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL11304571 | 0.79 | GRIN1 (0.43) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL18690743 | 0.79 | SCN2A (0.63) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL9633313 | 0.79 | GRIN2B (0.61) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL3692033 | 0.79 | GRIN2B (0.61) | GRIN2BGRIN1SIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253518-A1 | KINASE INHIBITOR | NISSAN CHEMICAL CORPORATION (JP) | 2021-08-19 | — | — | US | disclosed |
| US-20200165194-A1 | ADDITIVE COMPOSITION FOR CULTURE MEDIUM, ADDITIVE COMPOUND FOR CULTURE MEDIUM, AND METHOD FOR CULTURE OF CELLS OR TISSUE USING SAME | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-28 | — | — | US | disclosed |
| US-10544103-B2 | 5-HT2 antagonists | ANAMAR AB (SE) | 2020-01-28 | — | — | US | disclosed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |
| US-20040019094-A1 | Compounds acting as melanocortin receptor ligands | HPF IP HOLDING S.A. (LU) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019094-A1 | Compounds acting as melanocortin receptor ligands | MC1R, MC3R, MC5R | GRIN2B 554/4885GRIN1 419/4885SIGMAR1 160/4885 |
| US-20210253518-A1 | KINASE INHIBITOR | LATS2, LATS1, MAP3K6 | GRIN2B 2508/4885GRIN1 1437/4885SIGMAR1 3529/4885 |
| US-20200165194-A1 | ADDITIVE COMPOSITION FOR CULTURE MEDIUM, ADDITIVE COMPOUND FOR CULTURE MEDIUM, AND METHOD FOR CULTURE OF CELLS OR TISSUE USING SAME | NEFM, FGF2, FGF1 | GRIN2B 1119/4885GRIN1 1216/4885SIGMAR1 3242/4885 |
| US-10544103-B2 | 5-HT2 antagonists | HTR2B, HTR2C, HTR2A | GRIN2B 136/4885GRIN1 639/4885SIGMAR1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.