Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618371 | 1.00 | TSHR (0.36) | TSHRACHEHCAR2KDM4EMGLL | |
| SCHEMBL7767024 | 0.86 | HCAR2 (0.47) | TSHRHCAR2KDM4ENPSR1ALDH1A1 | |
| SCHEMBL7774728 | 0.86 | HCAR2 (0.47) | TSHRHCAR2KDM4ENPSR1ALDH1A1 | |
| SCHEMBL7767019 | 0.86 | HCAR2 (0.47) | TSHRHCAR2KDM4ENPSR1ALDH1A1 | |
| SCHEMBL22551695 | 0.86 | HCAR2 (0.43) | TSHRACHEHCAR2KDM4ENPSR1 | |
| SCHEMBL9618370 | 0.85 | TSHR (0.45) | TSHRACHEHCAR2MGLLNPSR1 | |
| SCHEMBL7770908 | 0.83 | HCAR2 (0.50) | TSHRACHEHCAR2KDM4ENPSR1 | |
| SCHEMBL7767056 | 0.83 | HCAR2 (0.50) | TSHRACHEHCAR2KDM4ENPSR1 | |
| SCHEMBL7767052 | 0.83 | HCAR2 (0.50) | TSHRACHEHCAR2KDM4ENPSR1 | |
| SCHEMBL7640896 | 0.82 | TSHR (0.38) | TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4332710-A | — | — | None | — | — | JP | disclosed |
| CN-102762340-A | Polishing pad and method of making the same | 3M INNOVATIVE PROPERTIES CO | 2012-10-31 | — | — | CN | disclosed |
| JP-H04332710-A | HYDROPHILIC RESIN | NIPPON OIL & FATS CO LTD | 1992-11-19 | — | — | JP | disclosed |