SCHEMBL7640896

SCHEMBL7640896

O=C(O)C=C(CCO)C(=O)OCCO

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9410884 0.87 KDM4E (0.39) TSHRKDM4E
SCHEMBL9618371 0.82 TSHR (0.36) TSHRKDM4E
SCHEMBL9628973 0.82 NPSR1 (0.42) TSHRKDM4E
SCHEMBL9471296 0.82 NPSR1 (0.42) TSHRKDM4E
SCHEMBL9618372 0.82 TSHR (0.36) TSHRKDM4E
SCHEMBL11457923 0.79 GPR84 (0.38) TSHRKDM4E
SCHEMBL27519547 0.76 MAPT (0.36)
SCHEMBL7770019 0.75 HCAR2 (0.41) TSHR
SCHEMBL1274405 0.75 HCAR2 (0.41) TSHR
SCHEMBL1274403 0.75 HCAR2 (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6465579-B1 OBTAINED BY REACTING A POLYMER HAVING A POLAR GROUP CONTAINING A HETERO ATOM AND A BENZENE RING, SUCH AS BUTADIENE-STYRENE-VINYLPYRIDINE TERPOLYMER, WITH SILICA; PROVIDES LOW VISCOSITY AND PROCESSABILITY TO RUBBER THE YOKOHAMA RUBBER CO., LTD. (JP) 2002-10-15 US disclosed