Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978269 | 0.85 | SMN1; SMN2 (0.70) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8366580 | 0.84 | PKM (0.63) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20425192 | 0.83 | PKM (0.62) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20425191 | 0.83 | PKM (0.62) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6278978 | 0.83 | SMN1; SMN2 (0.68) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9449637 | 0.81 | PKM (0.66) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30419025 | 0.81 | PKM (1.00) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL361312 | 0.81 | PKM (1.00) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9551407 | 0.80 | MAPT (0.70) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6284343 | 0.80 | PKM (0.64) | PKMSMN1; SMN2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4299987-A | — | — | None | — | — | JP | disclosed |
| JP-H04299987-A | PRODUCTION OF OPTICALLY ACTIVE INDOLE HYDROXY ACIDS | KAWAKEN FINE CHEM CO LTD | 1992-10-23 | — | — | JP | disclosed |