Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17063571 | 0.78 | GABRA1 (0.40) | GABRA1GABRB2KMT2AMEN1MAPT | |
| SCHEMBL10989031 | 0.77 | GABRA1 (0.50) | GABRA1GABRB2KMT2AMEN1MAPT | |
| SCHEMBL2316422 | 0.75 | GABRA1 (0.67) | GABRA1GABRB2ALDH1A1LMNA | |
| SCHEMBL10991179 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2KMT2AMEN1GAA | |
| SCHEMBL9325896 | 0.73 | GABRA1 (0.49) | GABRA1GABRB2KMT2AMEN1MAPT | |
| SCHEMBL28474947 | 0.72 | GABRA1 (0.50) | GABRA1GABRB2 | |
| SCHEMBL18244821 | 0.72 | GABRA1 (0.47) | GABRA1GABRB2 | |
| SCHEMBL5824091 | 0.71 | GABRA1 (0.58) | GABRA1GABRB2KMT2AMEN1MAPT | |
| SCHEMBL173300 | 0.70 | GABRA1 (0.56) | GABRA1GABRB2KMT2AMEN1MAPT | |
| SCHEMBL29763626 | 0.70 | GABRA1 (0.56) | GABRA1GABRB2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4312568-A | — | — | None | — | — | JP | disclosed |
| JP-H04312568-A | PRODUCTION OF N,N'-BIS(2,6-DIALKYLPHENYL)THIOUREA | KAWAGUCHI KAGAKU KOGYO KK | 1992-11-04 | — | — | JP | disclosed |