Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.63 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.52 |
| ▸ | CCNC | P24863 | 2/20 | 0.50 |
| ▸ | CDK8 | P49336 | 2/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30308690 | 0.97 | DYRK1A (0.65) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| SCHEMBL1896511 | 0.97 | DYRK1A (0.65) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| Iodide SCHEMBL28298350 | 0.91 | DYRK1A (0.60) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| Iodide SCHEMBL28741643 | 0.89 | DYRK1A (0.58) | DYRK1AUHRF1MAP4K4CDC7ROCK2 | |
| SCHEMBL8964255 | 0.87 | DYRK1A (0.62) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| SCHEMBL31119862 | 0.87 | DYRK1A (0.62) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| Hydrochloric Acid SCHEMBL30657718 | 0.85 | DYRK1A (0.60) | DYRK1AUHRF1MAP4K4CCNCCDK8 | |
| SCHEMBL30559511 | 0.85 | DYRK1A (0.60) | DYRK1AUHRF1MAP4K4CDC7ROCK2 | |
| SCHEMBL134658 | 0.85 | DYRK1A (0.60) | DYRK1AUHRF1MAP4K4CDC7ROCK2 | |
| SCHEMBL18674428 | 0.85 | UHRF1 (0.56) | DYRK1AUHRF1MAP4K4CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4337258-A | — | — | None | — | — | JP | disclosed |
| JP-H04337258-A | NONAQUEOUS ELECTROLYTE BATTERY | SANYO ELECTRIC CO LTD | 1992-11-25 | — | — | JP | disclosed |