SCHEMBL8964255

SCHEMBL8964255

Cc1cc(-c2ccncc2)ccn1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.62
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
UHRF1 Q96T88 1/20 0.52
HTT P42858 1/20 0.50
WNT3A P56704 3/20 0.49
NFATC1 O95644 1/20 0.49
PSEN1 P49768 2/20 0.48
PSEN2 P49810 2/20 0.48
APH1B Q8WW43 2/20 0.48
NCSTN Q92542 2/20 0.48
APH1A Q96BI3 2/20 0.48
PSENEN Q9NZ42 2/20 0.48
MAP4K4 O95819 1/20 0.47
PABPC1 P11940 1/20 0.46
APOBEC3A P31941 1/20 0.46
EIF4H Q15056 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
CCNC P24863 1/20 0.46
CDK8 P49336 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31119862 1.00 DYRK1A (0.62) DYRK1ALMNAMAPTUHRF1HTT
Hydrochloric Acid SCHEMBL30657718 0.98 DYRK1A (0.60) DYRK1ALMNAMAPTUHRF1HTT
Iodide SCHEMBL28298350 0.98 DYRK1A (0.60) DYRK1ALMNAMAPTUHRF1HTT
SCHEMBL30308690 0.90 DYRK1A (0.65) DYRK1AUHRF1WNT3ANFATC1PSEN1
SCHEMBL1896511 0.90 DYRK1A (0.65) DYRK1AUHRF1WNT3ANFATC1PSEN1
Iodide SCHEMBL9618570 0.87 DYRK1A (0.63) DYRK1AUHRF1WNT3ANFATC1PSEN1
SCHEMBL134658 0.84 DYRK1A (0.60) DYRK1AUHRF1WNT3APSEN1PSEN2
SCHEMBL30559511 0.84 DYRK1A (0.60) DYRK1AUHRF1WNT3APSEN1PSEN2
SCHEMBL6855459 0.84 DYRK1A (0.66) DYRK1AUHRF1WNT3APSEN1PSEN2
SCHEMBL18174668 0.84 DYRK1A (0.51) DYRK1AWNT3ANFATC1PSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110387036-A A kind of random polyarylether electrode active material and preparation method thereof containing purpurine side chain 福州大学 2019-10-29 CN claimed
CN-110305313-A A kind of purpurine functional poly aryl oxide electrode active material and preparation method thereof 福州大学 2019-10-08 CN claimed
CN-109796396-A A kind of preparation method of N- methyl -4,4 '-bipyridyl iodide 山西医科大学 2019-05-24 CN claimed
CN-103113876-B Photochromic optomagnetic material 中国科学院福建物质结构研究所 2017-02-08 CN claimed
CN-103113876-A Photochromic optomagnetic material FUJIAN MATTER STRUCTURE 2013-05-22 CN claimed
US-20250122402-A1 LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS PROMERUS, LLC (US) 2025-04-17 US disclosed
US-12162895-B2 DNA polymerase theta inhibitor for treatment of cancer BREAKPOINT THERAPEUTICS GMBH (DE) 2024-12-10 US disclosed
US-12145945-B2 Compounds, compositions, and therapeutic uses thereof BREAKPOINT THERAPEUTICS GMBH (DE) 2024-11-19 US disclosed
US-20240336628-A1 NOVEL COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF BREAKPOINT THERAPEUTICS GMBH (DE) 2024-10-10 US disclosed
US-20240327431-A1 DNA POLYMERASE THETA INHIBITOR FOR TREATMENT OF CANCER BREAKPOINT THERAPEUTICS GMBH (DE) 2024-10-03 US disclosed
US-20240327430-A1 NOVEL COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF BREAKPOINT THERAPEUTICS GMBH (DE) 2024-10-03 US disclosed
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
WO-2010107244-A2 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOW ADVANCED DISPLAY MATERIALS, LTD. (KR) 2010-09-23 WO disclosed
US-20090281311-A1 1,3,5-TRIAZINE DERIVATIVE, PRODUCTION METHOD THEREOF AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THIS AS A COMPOSING COMPONENT TOSOH CORPORATION (JP) 2009-11-12 US disclosed
US-20090281311-A1 1,3,5-TRIAZINE DERIVATIVE, PRODUCTION METHOD THEREOF AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THIS AS A COMPOSING COMPONENT TOSOH CORPORATION (JP) 2009-11-12 US disclosed
US-20090066223-A1 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-12 US disclosed
US-20090066223-A1 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-12 US disclosed
EP-1857521-A1 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR Mitsubishi Chemical Corporation (JP) 2007-11-21 EP disclosed
US-5516462-A VIOLOGEN COMPOUND; POTASSIUM SALT ELECTROLYTE AND SOLVENT MIXTURES; REVERSIBLE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1996-05-14 US disclosed
CN-88100754-A The Aquo-composition of cation compound and xanthene glue 1988-09-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162895-B2 DNA polymerase theta inhibitor for treatment of cancer POLQ, POLB, POLH DYRK1A 3264/4885LMNA 1602/4885MAPT 1209/4885
US-20240327430-A1 NOVEL COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF POLQ, POLK, POLB DYRK1A 4125/4885LMNA 1558/4885MAPT 1489/4885
US-20240336628-A1 NOVEL COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF POLQ, POLK, POLB DYRK1A 4125/4885LMNA 1558/4885MAPT 1489/4885
US-20240327431-A1 DNA POLYMERASE THETA INHIBITOR FOR TREATMENT OF CANCER POLQ, POLB, POLH DYRK1A 3264/4885LMNA 1602/4885MAPT 1209/4885
US-12145945-B2 Compounds, compositions, and therapeutic uses thereof POLQ, POLK, POLB DYRK1A 4090/4885LMNA 1116/4885MAPT 1441/4885
US-20090281311-A1 1,3,5-TRIAZINE DERIVATIVE, PRODUCTION METHOD THEREOF AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THIS AS A COMPOSING COMPONENT KCNJ2, KCNA4, KCNJ4 DYRK1A 3920/4885LMNA 4422/4885MAPT 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.