Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31070281 | 1.00 | GRM4 (0.45) | GRM4LMNAPARP10PARP11MAPT | |
| SCHEMBL27546357 | 0.98 | GRM4 (0.46) | GRM4LMNAPARP10PARP11MAPT | |
| Hydrochloric Acid SCHEMBL27470087 | 0.96 | GRM4 (0.45) | GRM4LMNAPARP10PARP11MAPT | |
| Hydrochloric Acid SCHEMBL29628896 | 0.96 | GRM4 (0.45) | GRM4LMNAPARP10PARP11MAPT | |
| SCHEMBL10199428 | 0.81 | GRM4 (0.58) | GRM4PARP10PARP11MAPTPIK3CA | |
| SCHEMBL25297274 | 0.78 | GRM4 (0.44) | GRM4MAPTFYNAURKB | |
| SCHEMBL30957760 | 0.78 | LMNA (0.39) | LMNAPARP10PARP11MAPTPDE3B | |
| SCHEMBL29264261 | 0.78 | LMNA (0.39) | LMNAPARP10PARP11MAPTPDE3B | |
| SCHEMBL10199341 | 0.75 | CYP2A6 (0.46) | GRM4FYNLRRK2 | |
| SCHEMBL10199363 | 0.75 | CYP2A6 (0.50) | GRM4LMNAPARP10PARP11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589101-A | Herbicides containing substituted thien-3-ylsulfonylamino (thio) carbonyltriazolin (thi) one compounds | BAYER CROPSCIENCE GMBH (DE) | 2005-03-02 | — | — | CN | claimed |
| JP-4337258-A | — | — | None | — | — | JP | disclosed |
| JP-H04337258-A | NONAQUEOUS ELECTROLYTE BATTERY | SANYO ELECTRIC CO LTD | 1992-11-25 | — | — | JP | disclosed |