Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239864 | 0.96 | KMT2A (0.48) | TSHRMAPK1KMT2AMEN1CETP | |
| SCHEMBL6241037 | 0.96 | KMT2A (0.48) | TSHRMAPK1KMT2AMEN1CETP | |
| SCHEMBL6232960 | 0.96 | KMT2A (0.48) | TSHRMAPK1KMT2AMEN1CETP | |
| SCHEMBL9550834 | 0.87 | CETP (0.43) | KMT2ACETPLMNAHTTPKM | |
| SCHEMBL25456811 | 0.84 | ALDH1A1 (0.32) | TSHRMAPK1KMT2AMEN1CETP | |
| SCHEMBL8597882 | 0.79 | HSD17B10 (0.54) | CETPHTTALDH1A1PKMHSD17B10 | |
| SCHEMBL28490061 | 0.78 | TSHR (0.43) | TSHRMAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL309704 | 0.77 | CETP (0.36) | CETPALDH1A1PKMHSD17B10 | |
| SCHEMBL309703 | 0.77 | CETP (0.36) | CETPALDH1A1PKMHSD17B10 | |
| SCHEMBL28310377 | 0.76 | TSHR (0.41) | TSHRMAPK1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4364148-A | — | — | None | — | — | JP | disclosed |
| JP-H04364148-A | POLYOL COMPOUND HAVING TRIFLUOROMETHYL GROUP AND ITS PRODUCTION | NIKKO KYODO CO LTD | 1992-12-16 | — | — | JP | disclosed |