SCHEMBL9619002

SCHEMBL9619002

NC(=O)SCCSC(N)=O.[Cu]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.42
HRH4 Q9H3N8 2/20 0.42
TDP1 Q9NUW8 4/20 0.40
LMNA P02545 3/20 0.33
CYP2C19 P33261 3/20 0.33
ALDH1A1 P00352 3/20 0.33
TSHR P16473 3/20 0.33
THPO P40225 2/20 0.33
OR51E2 Q9H255 1/20 0.33
NFKB1 P19838 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
HPGD P15428 2/20 0.32
ALOX15 P16050 2/20 0.32
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9085970 0.96 CYP1A2 (0.44) CYP1A2HRH4TDP1LMNACYP2C19
SCHEMBL4448372 0.93 CYP1A2 (0.42) CYP1A2HRH4TDP1LMNACYP2C19
SCHEMBL3687904 0.93 CYP1A2 (0.42) CYP1A2HRH4TDP1LMNACYP2C19
SCHEMBL3697213 0.93 CYP1A2 (0.42) CYP1A2HRH4TDP1LMNACYP2C19
Chloroform SCHEMBL9395259 0.84 TDP1 (0.41) CYP1A2HRH4TDP1ALDH1A1TSHR
SCHEMBL2746574 0.83 TDP1 (0.39) CYP1A2HRH4TDP1LMNACYP2C19
SCHEMBL2745916 0.83 TDP1 (0.39) CYP1A2HRH4TDP1LMNACYP2C19
SCHEMBL11649486 0.80
SCHEMBL8938892 0.80 TDP1 (0.37) CYP1A2HRH4TDP1CYP2C19ALDH1A1
SCHEMBL2753807 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0201279-B1 MARINE ANTI-FOULING PAINT COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1992-01-22 EP disclosed
EP-0204444-B1 BINDER FOR ANTI-FOULING PAINTS COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1989-08-02 EP disclosed
US-4752629-A PIGMENT, MARINE BIOCIDE, AND FILM-FORMING HYDROLYSABLE POLYMER BINDER INTERNATIONAL PAINT PUBLIC LIMITED COMPANY (GB) 1988-06-21 US disclosed
US-4675051-A Marine anti-fouling paint INTERNATIONAL PAINT PUBLIC LIMITED COMPANY (GB) 1987-06-23 US disclosed
EP-0204444-A1 Binder for anti-fouling paints COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1986-12-10 EP disclosed
EP-0201279-A2 Marine anti-fouling paint COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1986-11-12 EP disclosed