Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THPO | P40225 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9085970 | 0.96 | CYP1A2 (0.44) | CYP1A2HRH4TDP1LMNACYP2C19 | |
| SCHEMBL4448372 | 0.93 | CYP1A2 (0.42) | CYP1A2HRH4TDP1LMNACYP2C19 | |
| SCHEMBL9619002 | 0.93 | CYP1A2 (0.42) | CYP1A2HRH4TDP1LMNACYP2C19 | |
| SCHEMBL3697213 | 0.93 | CYP1A2 (0.42) | CYP1A2HRH4TDP1LMNACYP2C19 | |
| Chloroform SCHEMBL9395259 | 0.84 | TDP1 (0.41) | CYP1A2HRH4TDP1ALDH1A1TSHR | |
| SCHEMBL2745916 | 0.83 | TDP1 (0.39) | CYP1A2HRH4TDP1LMNACYP2C19 | |
| SCHEMBL2746574 | 0.83 | TDP1 (0.39) | CYP1A2HRH4TDP1LMNACYP2C19 | |
| SCHEMBL8938892 | 0.80 | TDP1 (0.37) | CYP1A2HRH4TDP1CYP2C19ALDH1A1 | |
| SCHEMBL11649486 | 0.80 | — | — | |
| SCHEMBL2753807 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916613-B2 | Synergistic insecticidal mixtures | BAYER CROPSCIENCE AG (DE) | 2014-12-23 | — | — | US | disclosed |
| US-20140243326-A1 | Synergistic Insecticidal Mixtures | BAYER CROPSCIENCE AG (DE) | 2014-08-28 | — | — | US | disclosed |
| US-20100197747-A1 | Synergistic Insecticidal Mixtures | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | US | disclosed |
| US-20080280953-A1 | Agents Used for the Treatment of Seeds | BAYER CROPSCIENCE AG (DE) | 2008-11-13 | — | — | US | disclosed |
| US-20070155797-A1 | Comprising thiodicarb and a chloronicotinyl; controlling animal pests | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
| US-20060128718-A1 | Tetrahydropyridazine derivatives having a pesticidal effect | BAYER CROPSCIENCE AG (DE) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280953-A1 | Agents Used for the Treatment of Seeds | TUBB3, TUBB, GUSB | CYP1A2 4296/4885HRH4 1868/4885TDP1 3242/4885 |
| US-20070155797-A1 | Comprising thiodicarb and a chloronicotinyl; controlling animal pests | DDT, TBCB, L3MBTL4 | CYP1A2 876/4885HRH4 3519/4885TDP1 1812/4885 |
| US-20140243326-A1 | Synergistic Insecticidal Mixtures | DDT, TBCB, PITPNB | CYP1A2 1096/4885HRH4 2413/4885TDP1 2339/4885 |
| US-20100197747-A1 | Synergistic Insecticidal Mixtures | DDT, TBCB, PITPNB | CYP1A2 1096/4885HRH4 2413/4885TDP1 2339/4885 |
| US-20060128718-A1 | Tetrahydropyridazine derivatives having a pesticidal effect | DDT, ACHE, RDX | CYP1A2 148/4885HRH4 191/4885TDP1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.