Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157010 | 0.87 | LIG1 (0.67) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL29457566 | 0.87 | MEN1 (0.72) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL2868140 | 0.87 | MEN1 (0.72) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL9729361 | 0.86 | MEN1 (0.62) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL489842 | 0.85 | TDP1 (0.59) | MEN1KMT2ARAB9ATDP1L3MBTL1 | |
| SCHEMBL9472920 | 0.85 | KDM4E (0.70) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL29417548 | 0.85 | TDP1 (0.59) | MEN1KMT2ARAB9ATDP1L3MBTL1 | |
| SCHEMBL21887391 | 0.85 | TDP1 (0.76) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL5380007 | 0.85 | LIG1 (0.89) | LIG1LMNAMEN1KMT2AMAPT | |
| SCHEMBL9243680 | 0.83 | MEN1 (0.58) | LIG1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467826-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | disclosed |
| EP-0456608-A2 | Essentially linear polymers | CIBA-GEIGY AG (CH) | 1991-11-13 | — | — | EP | disclosed |
| EP-0410929-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |