Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.62 |
| ▸ | FASN | P49327 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713698 | 0.93 | FASN (0.59) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL2868140 | 0.91 | MEN1 (0.72) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL29457566 | 0.91 | MEN1 (0.72) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL9619552 | 0.86 | LIG1 (0.65) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL144795 | 0.86 | ATM (0.74) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL22717015 | 0.84 | MEN1 (0.70) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL28605264 | 0.83 | CA12 (0.67) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL1758482 | 0.82 | LIG1 (0.63) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL7551892 | 0.82 | CA12 (0.61) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL189236 | 0.80 | CLK1 (0.75) | MEN1KMT2AFASNRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162510-A | Prepared by condensing phenolic compounds with a 1,2-naphthoquinonediazide-4-sulfonic acid halide and an organic acid halide | HOECHST CELANESE CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |