Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ESRRA | P11474 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.48 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619566 | 0.95 | MAPT (0.68) | RAB9AMAPTHPGDESRRAPARP10 | |
| SCHEMBL9619696 | 0.91 | HPGD (0.79) | RAB9AMAPTHPGDESRRAPARP10 | |
| SCHEMBL4787074 | 0.87 | HPGD (0.73) | RAB9AMAPTHPGDESRRAPARP10 | |
| SCHEMBL4100319 | 0.85 | HPGD (0.83) | RAB9AMAPTHPGDESRRAPARP10 | |
| SCHEMBL9701153 | 0.84 | PARP10 (0.55) | RAB9APARP10KMT2AMEN1NPC1 | |
| SCHEMBL23386082 | 0.83 | ESR1 (0.62) | PARP10HSD17B1KMT2AMEN1ESR1 | |
| SCHEMBL13692140 | 0.83 | MAPT (0.66) | RAB9AMAPTHPGDESRRAPARP10 | |
| SCHEMBL1177919 | 0.81 | KMT2A (0.58) | RAB9AMAPTHPGDHSD17B1KMT2A | |
| SCHEMBL23386311 | 0.81 | ESR1 (0.67) | PARP10KMT2AMEN1ESR1ESR2 | |
| SCHEMBL203697 | 0.81 | HPGD (1.00) | RAB9AMAPTHPGDESRRAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467826-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | disclosed |