SCHEMBL9619696

SCHEMBL9619696

CC(=O)c1ccc(Oc2ccc3cc(Oc4ccc(C(C)=O)cc4)ccc3c2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.79
MAPT P10636 2/20 0.79
RAB9A P51151 1/20 0.79
ESRRA P11474 1/20 0.60
SCN7A Q01118 1/20 0.52
KCNH2 Q12809 1/20 0.52
SCN9A Q15858 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GAA P10253 2/20 0.50
KDM4E B2RXH2 1/20 0.48
STS P08842 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
HTT P42858 1/20 0.48
PARP10 Q53GL7 3/20 0.48
PARP15 Q460N3 2/20 0.48
PARP14 Q460N5 2/20 0.48
KMT2A Q03164 2/20 0.48
PARP16 Q8N5Y8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4787074 0.96 HPGD (0.73) HPGDMAPTRAB9AESRRASCN7A
SCHEMBL9619566 0.93 MAPT (0.68) HPGDMAPTRAB9AESRRASCN7A
SCHEMBL9619563 0.91 RAB9A (0.66) HPGDMAPTRAB9AESRRASCN7A
SCHEMBL203697 0.89 HPGD (1.00) HPGDMAPTRAB9AESRRAL3MBTL1
SCHEMBL3301210 0.89 HPGD (1.00) HPGDMAPTRAB9AESRRAL3MBTL1
SCHEMBL3719405 0.87 MAPT (0.60) HPGDMAPTRAB9AESRRAKDM4E
SCHEMBL3720759 0.83 MAPT (0.55) HPGDMAPTRAB9AESRRAKDM4E
SCHEMBL9789228 0.83 MAPT (0.86) HPGDMAPTRAB9AESRRAL3MBTL1
SCHEMBL564525 0.82 RAB9A (0.70) HPGDMAPTRAB9AESRRAKDM4E
SCHEMBL14548335 0.82 HPGD (0.70) HPGDMAPTRAB9AESRRAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467826-A2 Linear polymers CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed