SCHEMBL961958

SCHEMBL961958

CC(N)N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)NC(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 18/20 0.46
DNMT1 P26358 1/20 0.44
ADORA1 P30542 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7749265 0.86 KIF11 (0.59) KIF11DNMT1
SCHEMBL15764473 0.78 ADORA1 (0.49) KIF11DNMT1ADORA1
SCHEMBL619354 0.77 PPARA (0.61) KIF11DNMT1ADORA1
SCHEMBL1530926 0.77 PPARA (0.61) KIF11DNMT1ADORA1
SCHEMBL21084961 0.77 PPARA (0.61) KIF11DNMT1ADORA1
SCHEMBL23154450 0.76 PPARA (0.52) KIF11ADORA1
SCHEMBL29924138 0.76 PPARA (0.49) KIF11DNMT1ADORA1
SCHEMBL28769011 0.76 PPARA (0.52) KIF11ADORA1
SCHEMBL28769009 0.76 PPARA (0.52) KIF11ADORA1
SCHEMBL28628939 0.76 ADORA1 (0.51) KIF11DNMT1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456749-B1 A SUBSTITUTED POLYVINYL ALCOHOL REAGENT PVAC MEDICAL TECH LTD (CY) 2021-07-14 EP disclosed
EP-3456749-A1 A SUBSTITUTED POLYVINYAL ALCOHOL REAGENT PVAC Medical Technologies Ltd. (CY) 2019-03-20 EP disclosed
EP-2254944-B1 COMPOSITION FOR THE FORMATION OF GELS PVAC MEDICAL TECH LTD (CY) 2018-12-19 EP disclosed
US-9585987-B2 Composition for the formation of gels PVAC MEDICAL TECHNOLOGIES LTD (CY) 2017-03-07 US disclosed
US-20110008444-A1 COMPOSITION FOR THE FORMATION OF GELS IPR-SYSTEMS SWEDEN AB (SE) 2011-01-13 US disclosed