SCHEMBL9619618

SCHEMBL9619618

Nc1ccc(O)c2c1C(=O)c1c(F)c(F)c(F)c(F)c1C2=O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 3/20 0.77
CSNK2B P67870 3/20 0.77
CSNK2A1 P68400 3/20 0.77
CSNK2A3 Q8NEV1 3/20 0.77
MEN1 O00255 6/20 0.59
KMT2A Q03164 6/20 0.59
HPGD P15428 4/20 0.59
TDP1 Q9NUW8 4/20 0.59
POLB P06746 4/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
CSNK1A1 P48729 2/20 0.59
CSNK1D P48730 2/20 0.59
CSNK1G1 Q9HCP0 2/20 0.59
BLM P54132 2/20 0.59
PABPC1 P11940 1/20 0.59
MCL1 Q07820 1/20 0.59
PLEC Q15149 1/20 0.59
THRB P10828 4/20 0.54
NQO1 P15559 1/20 0.53
CYP3A4 P08684 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29031600 0.88 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL504614 0.88 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL31158152 0.88 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL497324 0.88 CSNK2A2 (0.54) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL3843709 0.88 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL504063 0.88 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL11146282 0.88 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL498572 0.88 CSNK2A2 (1.00) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL9619698 0.88 THRB (0.70) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
Hydrochloric Acid SCHEMBL4191951 0.86 CSNK2A2 (0.95) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0183975-B1 5,6,7,8-TETRAFLUOROANTHRAQUINONE DERIVATIVES Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1992-01-29 EP claimed
US-4647411-A DISPERSE DYES AND PIGMENTS, COLORFASTNESS, HEAT RESISTANCE NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1987-03-03 US claimed
EP-0183975-A2 5,6,7,8-Tetrafluoroanthraquinone derivatives Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1986-06-11 EP claimed
EP-0183975-B1 5,6,7,8-TETRAFLUOROANTHRAQUINONE DERIVATIVES Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1992-01-29 EP disclosed
US-4647411-A DISPERSE DYES AND PIGMENTS, COLORFASTNESS, HEAT RESISTANCE NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1987-03-03 US disclosed
EP-0183975-A2 5,6,7,8-Tetrafluoroanthraquinone derivatives Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1986-06-11 EP disclosed