Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619732 | 0.87 | TAAR1 (0.42) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL9619820 | 0.87 | TAAR1 (0.42) | TAAR1MAPK1CYP2C19ALDH1A1ALOX15 | |
| SCHEMBL11683594 | 0.83 | TAAR1 (0.50) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL9619728 | 0.82 | TSHR (0.41) | TAAR1MAPK1ALDH1A1MAPTKMT2A | |
| SCHEMBL9619780 | 0.80 | TAAR1 (0.40) | TAAR1MAPK1CYP2C19HIF1A | |
| SCHEMBL9619807 | 0.79 | TAAR1 (0.47) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL11683785 | 0.77 | TAAR1 (0.54) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL10530728 | 0.76 | TAAR1 (0.52) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL8390156 | 0.76 | TAAR1 (0.52) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL10597393 | 0.76 | TAAR1 (0.52) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214842-B1 | ORGANOTIN COMPOUNDS AND PESTICIDES CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4935408-A | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4774235-A | MITICIDES | SHIONOGI & CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0214842-A2 | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |