Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716918 | 0.86 | TSHR (0.39) | TSHRALDH1A1TAAR1HTR2AHTR2C | |
| Bromide SCHEMBL9619764 | 0.83 | TSHR (0.37) | TSHRALDH1A1TAAR1HTR2AHTR2C | |
| SCHEMBL9619923 | 0.82 | TAAR1 (0.50) | ALDH1A1TAAR1MAPK1KMT2AMAPT | |
| SCHEMBL9619674 | 0.78 | PPARG (0.36) | ALDH1A1TAAR1MEN1KMT2AMAPT | |
| SCHEMBL9619732 | 0.75 | TAAR1 (0.42) | TSHRALDH1A1TAAR1MAPK1KIF11 | |
| SCHEMBL9619807 | 0.72 | TAAR1 (0.47) | TSHRALDH1A1TAAR1MAPK1KMT2A | |
| SCHEMBL9619820 | 0.71 | TAAR1 (0.42) | TSHRALDH1A1TAAR1HTR2AHTR2C | |
| SCHEMBL978014 | 0.71 | TSHR (0.48) | TSHRALDH1A1TAAR1HTR2AHTR2C | |
| SCHEMBL11683594 | 0.71 | TAAR1 (0.50) | ALDH1A1TAAR1MAPK1KMT2AMAPT | |
| SCHEMBL9534416 | 0.70 | TSHR (0.44) | TSHRALDH1A1TAAR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214842-B1 | ORGANOTIN COMPOUNDS AND PESTICIDES CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4935408-A | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4774235-A | MITICIDES | SHIONOGI & CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0214842-A2 | Organotin compounds and pesticides containing them | SHIONOGI & CO., LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |