Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669985 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| SCHEMBL9619966 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| SCHEMBL7429479 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| SCHEMBL8667999 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| SCHEMBL8668001 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| SCHEMBL7429468 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| SCHEMBL8669982 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| SCHEMBL7279284 | 1.00 | ELANE (0.48) | ELANEHSD17B10TDP1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL10932577 | 0.99 | ELANE (0.47) | ELANEHSD17B10TDP1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL10932585 | 0.99 | ELANE (0.47) | ELANEHSD17B10TDP1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| US-4734407-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | disclosed |
| US-4547573-A | BACTERICIDES | ICI PHARMA (FR) | 1985-10-15 | — | — | US | disclosed |
| US-4492694-A | ORAL ADMINISTRATION | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | disclosed |
| EP-0122157-A2 | Improvements in or relating to indolylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |
| US-4463173-A | ANTIBIOTIC, BACTERICIDE | ICI PHARMA (FR) | 1984-07-31 | — | — | US | disclosed |
| EP-0113965-A2 | Process for the preparation of cephalosporin derivatives | ICI PHARMA (FR) | 1984-07-25 | — | — | EP | disclosed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | disclosed |
| US-4438265-A | Esters of 7-sulfenyliminocephem-4-carboxylic acids | SANKYO COMPANY LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | disclosed |
| US-4162251-A | Process for the preparation of β-lactam compounds | SANKYO COMPANY LIMITED (JP) | 1979-07-24 | — | — | US | disclosed |
| US-4005074-A | Process for cleaving an imido side chain from penicillins and cephalosporins | ELI LILLY AND COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001239-A | CEPHALOSPORIN CLEAVAGE PROCESS | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3994888-A | Cephalosporin cleavage process | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |