Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | RNMT | O43148 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413282 | 1.00 | ADORA3 (0.74) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL2792380 | 0.91 | ADORA3 (0.68) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL21311160 | 0.89 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL6663002 | 0.88 | ADORA3 (0.71) | ADORA3ADORA1DOT1L | |
| SCHEMBL6662994 | 0.88 | ADORA3 (0.71) | ADORA3ADORA1DOT1L | |
| SCHEMBL21311440 | 0.88 | ADORA3 (0.64) | ADORA3ADORA1ADORA2AADORA2BDOT1L | |
| SCHEMBL23647923 | 0.87 | ADORA3 (0.72) | ADORA3ADORA1 | |
| SCHEMBL20801120 | 0.87 | ADORA3 (0.72) | ADORA3ADORA1 | |
| SCHEMBL40635 | 0.87 | ADORA3 (0.72) | ADORA3ADORA1 | |
| SCHEMBL40634 | 0.87 | ADORA3 (0.72) | ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269574-B1 | NOVEL ADENOSINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS AN ACTIVE INGREDIENT | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |