Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139538 | 0.83 | MEN1 (0.37) | MEN1USP2POLBMAPTIDE | |
| SCHEMBL9334331 | 0.77 | — | — | |
| SCHEMBL9337158 | 0.75 | MEN1 (0.32) | MEN1MAPTKMT2A | |
| SCHEMBL9620158 | 0.74 | — | — | |
| SCHEMBL7485753 | 0.66 | — | — | |
| SCHEMBL4303795 | 0.62 | MEN1 (0.43) | MEN1USP2POLBMAPTIDE | |
| SCHEMBL19086522 | 0.62 | — | — | |
| SCHEMBL10501263 | 0.59 | — | — | |
| SCHEMBL9505377 | 0.58 | CYP3A4 (0.35) | POLBKMT2A | |
| SCHEMBL27621996 | 0.58 | CYP3A4 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116861-A | Treatment of Hypertension and Angina Pectoris | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0437527-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1991-07-24 | — | — | EP | disclosed |
| WO-1990004603-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1990-05-03 | — | — | WO | disclosed |
| EP-0366171-A1 | Nucleoside derivatives | NYCOMED AS (NO) | 1990-05-02 | — | — | EP | disclosed |
| US-4746653-A | ANTAGONISTS OF N-METHYL-D-ASPARTATE SENSITIVE EXCITATORY AMINO ACID RECEPTOR; TREATMENT OF MUSCULAR SPASMS, CONVULSIVE DISORDERS AND ANXIETY | CIBA-GEIGY CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |