⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620253 | 0.80 | — | — | |
| SCHEMBL27493632 | 0.80 | — | — | |
| SCHEMBL6618960 | 0.70 | — | — | |
| SCHEMBL21362414 | 0.70 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL16789173 | 0.70 | MAPK1 (0.35) | — | |
| SCHEMBL37673 | 0.69 | — | — | |
| SCHEMBL25702185 | 0.69 | — | — | |
| SCHEMBL27551378 | 0.68 | MGAM (0.52) | — | |
| SCHEMBL6843702 | 0.67 | — | — | |
| SCHEMBL27964090 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178176-B1 | TETRAHYDRO-1,2,4-OXADIAZINE-5-THIONE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-01-02 | — | — | EP | disclosed |
| US-4755510-A | Novel anticonvulsive tetrahydro-1,2,4-oxadiazine-5-thion derivatives and use | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1988-07-05 | — | — | US | disclosed |
| EP-0178176-A2 | Tetrahydro-1,2,4-oxadiazine-5-thione derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | disclosed |