Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL14739642 | 0.96 | CA2 (0.75) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL17360710 | 0.92 | CA2 (0.88) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL2171327 | 0.92 | CA2 (0.88) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL31462035 | 0.90 | CA2 (0.92) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL8007689 | 0.89 | CA2 (0.75) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL11672845 | 0.88 | CA2 (0.81) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL689372 | 0.88 | CA2 (0.96) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL321981 | 0.88 | CA2 (0.96) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL6608444 | 0.88 | CA2 (0.96) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL15387920 | 0.88 | CA2 (0.96) | CA2NFKB1CYP3A4TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386000-B1 | CONTROLLED RELEASE OF ANTIBIOTIC SALTS FROM AN IMPLANT | THE UPJOHN COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| US-5079007-A | Mixture of amorphous and crystalline cephalosporin | THE UPJOHN COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| EP-0386000-A1 | CONTROLLED RELEASE OF ANTIBIOTIC SALTS FROM AN IMPLANT. | UPJOHN CO (US) | 1990-09-12 | — | — | EP | disclosed |
| WO-1989000852-A1 | CONTROLLED RELEASE OF ANTIBIOTIC SALTS FROM AN IMPLANT | THE UPJOHN COMPANY (US) | 1989-02-09 | — | — | WO | disclosed |