Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL10569620 | 0.78 | HCAR2 (0.44) | HCAR2HDAC4PRMT5WDR77POLB | |
| SCHEMBL9620281 | 0.74 | HCAR2 (0.47) | HCAR2HDAC4PRMT5WDR77LMNA | |
| SCHEMBL9620247 | 0.73 | HCAR2 (0.41) | HCAR2HDAC4PRMT5WDR77POLB | |
| SCHEMBL29277563 | 0.68 | HCAR2 (0.46) | HCAR2HDAC4PRMT5WDR77 | |
| SCHEMBL31644241 | 0.68 | HCAR2 (0.49) | HCAR2HDAC4PRMT5WDR77MAPK1 | |
| SCHEMBL10569611 | 0.68 | HCAR2 (0.39) | HCAR2HDAC4PRMT5WDR77LMNA | |
| SCHEMBL27096350 | 0.66 | HCAR2 (0.44) | HCAR2HDAC4PRMT5WDR77RAB9A | |
| SCHEMBL23278388 | 0.65 | HCAR2 (0.38) | HCAR2LMNAPIK3CDKMT2AL3MBTL1 | |
| SCHEMBL22572031 | 0.65 | HCAR2 (0.38) | HCAR2LMNAPIK3CDKMT2AL3MBTL1 | |
| SCHEMBL19723890 | 0.65 | HCAR2 (0.41) | HCAR2HDAC4PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292122-B1 | CYCLOHEXADIONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND SELECTIVE HERBICIDAL COMPOSITIONS AS WELL AS HERBICIDAL METHOD | NIHON NOHYAKU CO., LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0292122-A1 | Cyclohexadione derivatives, process for preparing the same and selective herbicidal compositions as well as herbicidal method | NIHON NOHYAKU CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |