SCHEMBL9620280

SCHEMBL9620280

COC(=O)c1c(Cl)cccc1S(N)(=O)=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.57
CA2 P00918 5/20 0.57
CA9 Q16790 5/20 0.57
CA5A P35218 1/20 0.57
CA12 O43570 4/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
KMT2A Q03164 2/20 0.47
GAA P10253 4/20 0.44
LMNA P02545 2/20 0.44
TSHR P16473 2/20 0.44
HTT P42858 1/20 0.44
POLB P06746 3/20 0.43
PTGES2 Q9H7Z7 5/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
GLA P06280 2/20 0.42
HPGD P15428 2/20 0.42
CASP1 P29466 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7287987 0.85 CA1 (0.47) CA1CA2CA9CA5ACA12
SCHEMBL22827733 0.82 CA1 (0.58) CA1CA2CA9CA5ACA12
SCHEMBL7339510 0.82 CA2 (0.73) CA1CA2CA9CA5ACA12
SCHEMBL29880091 0.82 CA1 (0.58) CA1CA2CA9CA5ACA12
SCHEMBL9620273 0.81 CA1 (0.57) CA1CA2CA9CA5ACA12
SCHEMBL28870596 0.81 CA2 (0.71) CA1CA2CA9CA5ACA12
SCHEMBL9143312 0.81 CA1 (0.57) CA1CA2CA9CA5ACA12
SCHEMBL517538 0.80 CA12 (0.61) CA1CA2CA9CA12CA7
SCHEMBL22827922 0.80 CA1 (0.42) CA1CA2CA9CA5ACA12
SCHEMBL1725976 0.80 KMT2A (0.47) CA1CA2CA9CA5ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104441-A HERBICIDAL SULFONAMIDES AND THEIR USE TO INFLUENCE PLANT GROWTH BASF AKTIENGESELLSCHAFT (DE) 1992-04-14 US disclosed
US-5100459-A Herbicides, plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
US-5032167-A Herbicides BASF (DE) 1991-07-16 US disclosed