Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728701 | 0.83 | FLT3 (0.67) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL12827003 | 0.81 | FLT3 (0.59) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL370573 | 0.78 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL5639746 | 0.78 | FLT3 (0.64) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL31277139 | 0.78 | FLT3 (0.77) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL31060426 | 0.78 | FLT3 (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| SCHEMBL28414304 | 0.77 | IDO1 (0.64) | FLT3KDM4EMAPTDAOHPGD | |
| Indole-2-Carboxylic Acid SCHEMBL1935 | 0.76 | KDM4E (1.00) | FLT3KDM4EMAPTDAOHPGD | |
| Methane SCHEMBL22343918 | 0.76 | FLT3 (0.96) | FLT3KDM4EMAPTDAOHPGD | |
| Indole-2-Carboxylic Acid SCHEMBL29395165 | 0.76 | KDM4E (1.00) | FLT3KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315902-B1 | BIS-INDOLYL ETHYLENE ALDEHYDES | BAYER AG (DE) | 1992-03-18 | — | — | EP | claimed |
| US-4902806-A | DYESTUFF INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-20 | — | — | US | claimed |
| EP-0315902-A1 | Bis-indolyl ethylene aldehydes | BAYER AG (DE) | 1989-05-17 | — | — | EP | claimed |
| EP-0315902-B1 | BIS-INDOLYL ETHYLENE ALDEHYDES | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0315902-B1 | BIS-INDOLYL ETHYLENE ALDEHYDES | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0315902-A1 | Bis-indolyl ethylene aldehydes | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0315902-A1 | Bis-indolyl ethylene aldehydes | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0315902-A1 | Bis-indolyl ethylene aldehydes | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |