SCHEMBL9512829

SCHEMBL9512829

C=C[Si](C)(C)CCCOc1ccc2nn(-c3cc(OC)cc(C(C)(C)C)c3O)nc2c1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MAPT P10636 4/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
TP53 P04637 2/20 0.31
RXFP1 Q9HBX9 1/20 0.31
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2801917 0.96 CA1 (0.34) CA1CA2MAPTLMNAALDH1A1
SCHEMBL9513087 0.87 KDM4E (0.32)
SCHEMBL9620532 0.86 CA1 (0.42) CA1CA2MAPTLMNAALDH1A1
SCHEMBL8441278 0.82 CA1 (0.39) CA1CA2MAPTLMNAALDH1A1
SCHEMBL1247781 0.82 CA1 (0.39) CA1CA2MAPTLMNAALDH1A1
SCHEMBL21302457 0.81 CA1 (0.33) CA1CA2MAPTLMNATP53
SCHEMBL8922405 0.81 CA1 (0.40) CA1CA2MAPTLMNAALDH1A1
SCHEMBL3879963 0.81 POLB (0.39) CA1CA2MAPTLMNAALDH1A1
SCHEMBL18987341 0.80 CA1 (0.40) CA1CA2MAPTLMNAALDH1A1
SCHEMBL1517392 0.78 MAOA (0.32) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282294-B1 Vinylsilylalkoxy arylbenzotriazole compounds and UV absorbing compositions made therefrom IOLAB CORP (US) 1993-12-01 EP claimed
US-4803254-A Vinylsilylalkoxy arylbenzotriazole compounds and UV absorbing compositions made therefrom IOLAB CORPORATION (US) 1989-02-07 US claimed
EP-0282294-B1 Vinylsilylalkoxy arylbenzotriazole compounds and UV absorbing compositions made therefrom IOLAB CORP (US) 1993-12-01 EP disclosed