Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 13/20 | 0.66 |
| ▸ | KDR | P35968 | 5/20 | 0.54 |
| ▸ | FLT3 | P36888 | 3/20 | 0.53 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959982 | 0.93 | PRKD1 (0.64) | PRKD1KDRFLT3AURKARET | |
| SCHEMBL6923109 | 0.89 | HRH3 (0.65) | PRKD1KDRRET | |
| SCHEMBL1079502 | 0.88 | PRKD1 (0.70) | PRKD1 | |
| SCHEMBL959960 | 0.84 | PRKD1 (0.58) | PRKD1 | |
| SCHEMBL936788 | 0.84 | PRKD1 (0.65) | PRKD1KDRRET | |
| SCHEMBL1053391 | 0.84 | PRKD1 (0.70) | PRKD1 | |
| SCHEMBL960488 | 0.84 | PRKD1 (0.70) | PRKD1 | |
| SCHEMBL6924065 | 0.83 | PRKD1 (0.64) | PRKD1KDRRET | |
| SCHEMBL6924052 | 0.83 | PRKD1 (0.69) | PRKD1 | |
| SCHEMBL1056077 | 0.81 | PRKD1 (0.76) | PRKD1AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |