SCHEMBL9620769

SCHEMBL9620769

CC=CCC(=O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.45
CYP19A1 P11511 1/20 0.45
KMT2A Q03164 3/20 0.44
MAPT P10636 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
EGFR P00533 1/20 0.42
ERBB2 P04626 1/20 0.42
TDP1 Q9NUW8 3/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
ALOX15 P16050 2/20 0.38
AKT1 P31749 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10701813 1.00 ELANE (0.45) ELANECYP19A1KMT2AMAPTALDH1A1
SCHEMBL10577041 1.00 ELANE (0.45) ELANECYP19A1KMT2AMAPTALDH1A1
SCHEMBL17138187 0.87 KMT2A (0.46) KMT2AMAPTALDH1A1HSD17B10LMNA
SCHEMBL17138184 0.87 KMT2A (0.46) KMT2AMAPTALDH1A1HSD17B10LMNA
SCHEMBL7693338 0.85 ELANE (0.47) ELANECYP19A1KMT2AMAPTALDH1A1
SCHEMBL10959548 0.84 ELANE (0.47) ELANECYP19A1KMT2AMAPTALDH1A1
SCHEMBL10000490 0.84 PRSS1 (0.49) ELANECYP19A1KMT2AMAPTALDH1A1
SCHEMBL10959282 0.84 PRSS1 (0.49) ELANECYP19A1KMT2AMAPTALDH1A1
SCHEMBL10959541 0.84 ELANE (0.47) ELANECYP19A1KMT2AMAPTALDH1A1
SCHEMBL4888627 0.83 CYP19A1 (0.46) ELANECYP19A1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4537987-A Preparation of pure monoesters of adipic acid BASF AKTIENGESELLSCHAFT (DE) 1985-08-27 US claimed
CN-105777463-B A kind of β, γ-beta-unsaturated esters compound preparation method 大连理工大学 2019-01-18 CN disclosed
CN-105777463-A Preparation method of beta, gamma-unsaturated ester compound 大连理工大学 2016-07-20 CN disclosed
EP-0269045-B1 PROCESS FOR PREPARING ETHERIFED 3-HYDROXY VALERIC ACID ESTERS BASF Aktiengesellschaft (DE) 1992-01-02 EP disclosed
US-4791219-A Preparation of etherified 3-hydroxyvalerates BASF AKTIENGESELLSCHAFT (DE) 1988-12-13 US disclosed
US-4537987-A Preparation of pure monoesters of adipic acid BASF AKTIENGESELLSCHAFT (DE) 1985-08-27 US disclosed
US-4537724-A Alkanoyloxybenzenesulfonate salt production ETHYL CORPORATION (US) 1985-08-27 US disclosed
EP-0131860-A2 Process for the production of pure adipinic-acid monoesters BASF Aktiengesellschaft (DE) 1985-01-23 EP disclosed