Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.59 |
| ▸ | MAOA | P21397 | 13/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429220 | 0.92 | MAOB (0.51) | MAOBMAOAMRGPRX4 | |
| SCHEMBL7278343 | 0.86 | MAOA (0.68) | MAOBMAOAMRGPRX4 | |
| SCHEMBL9621181 | 0.83 | MAOA (0.57) | MAOBMAOA | |
| SCHEMBL9620526 | 0.83 | MAOA (0.57) | MAOBMAOA | |
| SCHEMBL20234906 | 0.82 | MAOA (0.62) | MAOBMAOAMRGPRX4 | |
| SCHEMBL5713217 | 0.81 | MAOA (0.61) | MAOBMAOA | |
| SCHEMBL11147426 | 0.81 | MAOA (0.61) | MAOBMAOA | |
| SCHEMBL4192600 | 0.80 | MAOB (0.56) | MAOBMAOAMRGPRX4 | |
| SCHEMBL10880568 | 0.78 | MAOA (0.58) | MAOBMAOAMRGPRX4 | |
| SCHEMBL3451690 | 0.77 | MAOB (0.94) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284359-B1 | 1,4-DISUBSTITUTED PIPERAZINE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4880809-A | HYPOTENSIVE AGENTS, AMIDE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0284359-A1 | 1,4-Disubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |