SCHEMBL9621032

SCHEMBL9621032

CCN(CC)c1ccc(-c2nc(-c3ccc(N(CC)CC)cc3)c(-c3ccc(N(CC)CC)cc3)o2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 4/20 0.45
MAPK13 O15264 2/20 0.45
MAPK12 P53778 2/20 0.45
MAPK11 Q15759 2/20 0.45
GCGR P47871 1/20 0.45
HDAC6 Q9UBN7 1/20 0.44
ALDH1A1 P00352 7/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
PSMD14 O00487 1/20 0.39
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
GFER P55789 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TERT O14746 1/20 0.39
KDM4E B2RXH2 6/20 0.38
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
MAPT P10636 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15437400 0.94 MAPK13 (0.46) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL8648399 0.94 MAPK13 (0.46) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL9246250 0.90 KDM4E (0.43) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL9707139 0.89 NOX1 (0.45) MAPK14MAPK13MAPK12MAPK11ALDH1A1
SCHEMBL9707136 0.89 NOX1 (0.45) MAPK14MAPK13MAPK12MAPK11ALDH1A1
SCHEMBL9707142 0.88 SMN1; SMN2 (0.47) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL9707203 0.86 NR4A2 (0.40) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL11750003 0.83 ALDH1A1 (0.38) HDAC6ALDH1A1L3MBTL1CYP3A4MAPK1
SCHEMBL4651446 0.82 NR4A2 (0.46) HDAC6ALDH1A1L3MBTL1MAPK1TSHR
SCHEMBL6819831 0.82 NR4A2 (0.46) HDAC6ALDH1A1L3MBTL1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0234247-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND ELECTROPHOTOGRAPHIC PROCESS MITSUBISHI PAPER MILLS, LTD. (JP) 1992-01-08 EP disclosed
US-4702983-A Electrophotographic photoreceptor comprising bis-azo pigment MITSUBISHI PAPER MILLS, LTD. (JP) 1987-10-27 US disclosed
EP-0234247-A2 Electrophotographic photoreceptor and electrophotographic process MITSUBISHI PAPER MILLS, LTD. (JP) 1987-09-02 EP disclosed