Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621144 | 1.00 | TSHR (0.58) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL9621056 | 0.99 | TSHR (0.56) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL10832806 | 0.99 | TSHR (0.56) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL10832803 | 0.99 | TSHR (0.56) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL9621053 | 0.99 | TSHR (0.56) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL9620652 | 0.95 | SPHK1 (0.50) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL9620655 | 0.95 | SPHK1 (0.50) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL10725313 | 0.94 | SPHK1 (0.49) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL10725323 | 0.94 | SPHK1 (0.49) | TSHRHSD17B10SPHK1SPHK2MAOA | |
| SCHEMBL10725317 | 0.94 | SPHK1 (0.49) | TSHRHSD17B10SPHK1SPHK2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283490-B1 | PROCESS FOR THE PRODUCTION OF ETHANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-01-08 | — | — | EP | disclosed |
| EP-0283490-A1 | PROCESS FOR THE PRODUCTION OF ETHANE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1988-09-28 | — | — | EP | disclosed |
| WO-1988002364-A2 | PROCESS FOR THE PRODUCTION OF ETHANE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-04-07 | — | — | WO | disclosed |