Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 17/20 | 0.71 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.71 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.71 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621189 | 1.00 | ABCC9 (0.71) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9621182 | 1.00 | ABCC9 (0.71) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7319009 | 0.88 | ABCC9 (0.63) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7319016 | 0.88 | ABCC9 (0.63) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL122345 | 0.87 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9581581 | 0.87 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9581590 | 0.87 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9130135 | 0.86 | ABCC9 (0.71) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9130144 | 0.86 | ABCC9 (0.71) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9130150 | 0.86 | ABCC9 (0.71) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176689-B1 | BENZOPYRAN COMPOUNDS FOR THE TREATMENT OF SMOOTH MUSCLES CONTRACTION | BEECHAM GROUP PLC (GB) | 1992-04-01 | — | — | EP | claimed |
| EP-0176689-A2 | Benzopyran compounds for the treatment of smooth muscles contraction | BEECHAM GROUP PLC (GB) | 1986-04-09 | — | — | EP | claimed |
| US-4446113-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1984-05-01 | — | — | US | claimed |
| EP-0076075-A1 | Pharmaceutically active benzopyran compounds | BEECHAM GROUP PLC (GB) | 1983-04-06 | — | — | EP | claimed |
| EP-0120427-B1 | 3,4-Dihydro-thiaoxo-1-pyrrolidinyl-or piperidinyl-ZH-benzo[b]pyrons | BEECHAM GROUP PLC (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4786639-A | ADMINISTERING BENZOPYRAN DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1988-11-22 | — | — | US | disclosed |
| US-4647670-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-03-03 | — | — | US | disclosed |
| EP-0093535-B1 | NOVEL CHROMENES AND CHROMANS | BEECHAM GROUP PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4610992-A | Trans-4-(2-thiaoxo-1-pyrrolidinyl or piperidinyl)-2H-benzo[b]pyran-3-ol derivatives useful in treating hypertension | BEECHAM GROUP P.L.C. (GB) | 1986-09-09 | — | — | US | disclosed |
| EP-0176689-A2 | Benzopyran compounds for the treatment of smooth muscles contraction | BEECHAM GROUP PLC (GB) | 1986-04-09 | — | — | EP | disclosed |
| US-4510152-A | Antihypertensive chromenes and chromans | BEECHAM GROUP P.L.C. (GB) | 1985-04-09 | — | — | US | disclosed |
| EP-0120427-A1 | 3,4-Dihydro-thiaoxo-1-pyrrolidinyl-or piperidinyl-ZH-benzo[b]pyrons | BEECHAM GROUP PLC (GB) | 1984-10-03 | — | — | EP | disclosed |
| US-4446113-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1984-05-01 | — | — | US | disclosed |
| EP-0093535-A1 | Novel chromenes and chromans | BEECHAM GROUP PLC (GB) | 1983-11-09 | — | — | EP | disclosed |
| EP-0076075-A1 | Pharmaceutically active benzopyran compounds | BEECHAM GROUP PLC (GB) | 1983-04-06 | — | — | EP | disclosed |