Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10576060 | 0.99 | ALDH1A1 (0.65) | POLBALDH1A1HPGDCYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL9620800 | 0.86 | GAA (0.78) | POLBALDH1A1KDM4EGAAMEN1 | |
| Hydrochloric Acid SCHEMBL9620531 | 0.85 | GAA (0.64) | POLBALDH1A1HPGDCYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL9621025 | 0.84 | POLB (0.70) | POLBALDH1A1HPGDCYP2C9CYP3A4 | |
| SCHEMBL10334852 | 0.84 | ALDH1A1 (0.63) | POLBALDH1A1HPGDCYP3A4KDM4E | |
| SCHEMBL10520895 | 0.83 | POLB (0.83) | POLBALDH1A1CYP2C9CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL10334854 | 0.82 | POLB (0.81) | POLBALDH1A1CYP2C9CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL9620913 | 0.81 | KDM4E (0.69) | POLBALDH1A1CYP2C9CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL10334544 | 0.81 | GRIN2B (0.64) | POLBALDH1A1HPGDCYP2C9CYP3A4 | |
| SCHEMBL15303789 | 0.80 | KDM4E (0.83) | POLBALDH1A1CYP2C9KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284359-B1 | 1,4-DISUBSTITUTED PIPERAZINE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |